Serveur d'exploration Chloroquine

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Compliance to recommendations for the management of curative treatment of Plasmodium vivax/ovale infections.

Identifieur interne : 000F95 ( Main/Exploration ); précédent : 000F94; suivant : 000F96

Compliance to recommendations for the management of curative treatment of Plasmodium vivax/ovale infections.

Auteurs : J-F Faucher [France] ; A-P Bellanger [France] ; N. Shaniya ; L. Hustache-Mathieu [France] ; B. Hoen [France] ; C. Chirouze [France]

Source :

RBID : Hal:hal-01115459

Abstract

We assessed the compliance to recommendations for the routine management of Plasmodium vivax/ovale malaria, and analyzed the impact of discrepancies on the quality of care. We reviewed the cases of P. ovale and P. vivax malaria treated at the Besançon University Hospital, France (2008-2013). Chloroquine was prescribed in 44% of the 18 cases (4 due to P. ovale, 14 to P. vivax). Radical cure with primaquine was prescribed after the first bout of malaria for 6 patients. The primaquine dose prescribed was inferior to the recommended one for 4 patients. The mean delay between schizonticide treatment and primaquine cure was 43 days. The delay before access to primaquine radical cure was the only parameter, likely to alter treatment effectiveness, but also difficult to shorten. Future national guidelines should take into account that not all patients have access to primaquine treatment immediately after schizonticide treatment.


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Le document en format XML

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<idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
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<tutelle active="#struct-458810" type="direct">
<org type="institution" xml:id="struct-458810" status="VALID">
<idno type="IdRef">026403188</idno>
<idno type="ISNI">0000 0001 2188 3779 </idno>
<orgName>Université de Franche-Comté</orgName>
<orgName type="acronym">UFC</orgName>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-fcomte.fr</ref>
</desc>
</org>
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<tutelle active="#struct-426438" type="direct">
<org type="regroupinstitution" xml:id="struct-426438" status="VALID">
<idno type="IdRef">200716271</idno>
<orgName>Université Bourgogne Franche-Comté [COMUE]</orgName>
<orgName type="acronym">UBFC</orgName>
<date type="start">2015-04-01</date>
<desc>
<address>
<country key="FR"></country>
</address>
<ref type="url">http://www.ubfc.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
<placeName>
<settlement type="city" wicri:auto="siege">Besançon</settlement>
<region type="region" nuts="2">Franche-Comté</region>
</placeName>
<orgName type="university">Université de Franche-Comté</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Bourgogne Franche-Comté</orgName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Médecine et Maladies Infectieuses</title>
<idno type="ISSN">0399-077X</idno>
<imprint>
<date type="datePub">2014-07-31</date>
</imprint>
</series>
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<div type="abstract" xml:lang="en">
<p>We assessed the compliance to recommendations for the routine management of Plasmodium vivax/ovale malaria, and analyzed the impact of discrepancies on the quality of care. We reviewed the cases of P. ovale and P. vivax malaria treated at the Besançon University Hospital, France (2008-2013). Chloroquine was prescribed in 44% of the 18 cases (4 due to P. ovale, 14 to P. vivax). Radical cure with primaquine was prescribed after the first bout of malaria for 6 patients. The primaquine dose prescribed was inferior to the recommended one for 4 patients. The mean delay between schizonticide treatment and primaquine cure was 43 days. The delay before access to primaquine radical cure was the only parameter, likely to alter treatment effectiveness, but also difficult to shorten. Future national guidelines should take into account that not all patients have access to primaquine treatment immediately after schizonticide treatment.</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>France</li>
</country>
<region>
<li>Franche-Comté</li>
</region>
<settlement>
<li>Besançon</li>
</settlement>
<orgName>
<li>Université de Bourgogne Franche-Comté</li>
<li>Université de Franche-Comté</li>
</orgName>
</list>
<tree>
<noCountry>
<name sortKey="Shaniya, N" sort="Shaniya, N" uniqKey="Shaniya N" first="N" last="Shaniya">N. Shaniya</name>
</noCountry>
<country name="France">
<noRegion>
<name sortKey="Faucher, J F" sort="Faucher, J F" uniqKey="Faucher J" first="J-F" last="Faucher">J-F Faucher</name>
</noRegion>
<name sortKey="Bellanger, A P" sort="Bellanger, A P" uniqKey="Bellanger A" first="A-P" last="Bellanger">A-P Bellanger</name>
<name sortKey="Chirouze, C" sort="Chirouze, C" uniqKey="Chirouze C" first="C" last="Chirouze">C. Chirouze</name>
<name sortKey="Hoen, B" sort="Hoen, B" uniqKey="Hoen B" first="B" last="Hoen">B. Hoen</name>
<name sortKey="Hustache Mathieu, L" sort="Hustache Mathieu, L" uniqKey="Hustache Mathieu L" first="L" last="Hustache-Mathieu">L. Hustache-Mathieu</name>
</country>
</tree>
</affiliations>
</record>

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